Inhibition of sirtuins 1 and 2 impairs cell survival and migration and modulates the expression of P-glycoprotein and MRP3 in hepatocellular carcinoma cell lines

María Paula Ceballos, Giulia Decándido, Ariel D. Quiroga, +9

Toxicology Letters

Tumor MicroenvironmentImpairs Cell SurvivalLiver PhysiologyCell DeathSirtuins 1 +9

ACBP/DBI protein neutralization confers autophagy-dependent organ protection through inhibition of cell loss, inflammation, and fibrosis

Omar Motiño, Flavia Lambertucci, Gerasimos Anagnostopoulos, +19

Proceedings of the National Academy of Sciences

Diethylnitrosamine Increases Proliferation in Early Stages of Hepatic Carcinogenesis in Insulin-Treated Type 1 Diabetic Mice

Ainelén Arboatti, Flavia Lambertucci, M.G. Sedlmeier, +6

BioMed Research International

Hepatic CarcinogenesisDiabetic MiceImmunologyPathologyCell Death +19

High plasma concentrations of acyl‐coenzyme A binding protein (<scp>ACBP</scp>) predispose to cardiovascular disease: Evidence for a phylogenetically conserved proaging function of <scp>ACBP</scp>

Léa Montégut, Adrien Joseph, Hui Chen, +14

Aging Cell

MitophagyAgingMolecular BiologyBiogerontologyCardiovascular Translational Research +19

Full-Spectrum CARS Microscopy of Cells and Tissues with Ultrashort White-Light Continuum Pulses

Federico Vernuccio, Renzo Vanna, Chiara Ceconello, +11

The Journal of Physical Chemistry B

Disruption of tumor necrosis factor alpha receptor 1 signaling accelerates NAFLD progression in mice upon a high-fat diet

Flavia Lambertucci, Ainelén Arboatti, M.G. Sedlmeier, +12

The Journal of Nutritional Biochemistry

ObesityMetabolic SyndromeInflammationTumor Necrosis FactorChronic Inflammation +8

Benznidazole, the trypanocidal drug used for Chagas disease, induces hepatic NRF2 activation and attenuates the inflammatory response in a murine model of sepsis

Flavia Lambertucci, Omar Motiño, Silvina R. Villar, +8

Toxicology and Applied Pharmacology

InflammationAnti-inflammatoryHealth SciencesAfrican TrypanosomiasisMedicine +12

An obesogenic feedforward loop involving PPARγ, acyl-CoA binding protein and GABAA receptor

Gerasimos Anagnostopoulos, Omar Motiño, Sijing Li, +20

Cell Death and Disease

Acyl-coenzyme a binding protein (ACBP) - a risk factor for cancer diagnosis and an inhibitor of immunosurveillance

Léa Montégut, Peng Liu, Liwei Zhao, +31

Molecular Cancer

Autoimmune DiseaseMedicineImmunologyMolecular BiologyCancer Diagnosis +5

Lysosomal damage due to cholesterol accumulation triggers immunogenic cell death

Karla Alvarez-Valadez, Allan Sauvat, Julien Diharce, +16

Autophagy