Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosis

Shinji Tsutsumi, Tomomi Gotoh, Wataru Tomisato, +7

Cell Death and Differentiation

InflammationReductive StressAnti-inflammatoryAutoimmune DiseaseMedicine +10

Prostaglandin E2 Protects Gastric Mucosal Cells from Apoptosis via EP2 and EP4 Receptor Activation

Tatsuya Hoshino, Shinji Tsutsumi, Wataru Tomisato, +3

Journal of Biological Chemistry

MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands

Katharina Brandl, Lei Sun, Christina Neppl, +8

Proceedings of the National Academy of Sciences

Role of direct cytotoxic effects of NSAIDs in the induction of gastric lesions

Wataru Tomisato, Shinji Tsutsumi, Tatsuya Hoshino, +4

Biochemical Pharmacology

InflammationAnti-inflammatoryAnti-inflammatory AgentsGastrointestinal PharmacologyMedicine +7

Involvement of Intracellular Ca2+ Levels in Nonsteroidal Anti-inflammatory Drug-induced Apoptosis

Ken‐ichiro Tanaka, Wataru Tomisato, Tatsuya Hoshino, +7

Journal of Biological Chemistry

NSAIDs induce both necrosis and apoptosis in guinea pig gastric mucosal cells in primary culture

Wataru Tomisato, Shinji Tsutsumi, Kazuhito Rokutan, +2

American Journal of Physiology-Gastrointestinal and Liver Physiology

InflammationAnti-inflammatoryGastric Mucosal CellsMedicineApoptosis +9

Membrane permeabilization by non-steroidal anti-inflammatory drugs

Wataru Tomisato, Ken‐ichiro Tanaka, Takashi Katsu, +10

Biochemical and Biophysical Research Communications

InflammationMedicineMembrane TransportMembrane PermeabilizationMembrane System +3

iRhom2 is required for the secretion of mouse TNFα

Owen M. Siggs, Nengming Xiao, Ying Wang, +5

Blood

The NOTCH–FOXM1 Axis Plays a Key Role in Mitochondrial Biogenesis in the Induction of Human Stem Cell Memory–like CAR-T Cells

Taisuke Kondo, Makoto Ando, Nao Nagai, +14

Cancer Research

Induction of Claudin-4 by Nonsteroidal Anti-inflammatory Drugs and Its Contribution to Their Chemopreventive Effect

Shinji Mima, Shinji Tsutsumi, Hironori Ushijima, +9

Cancer Research