Guido Kurz

ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia

Tamara Maes, Cristina Mascaró, Iñigo Tirapu et al. · Cancer Cell · 2018 · 326 citations · Full text

Hematological Malignancy, Medicine, Drug Discovery +8

Arylsulfonamidothiazoles as a New Class of Potential Antidiabetic Drugs. Discovery of Potent and Selective Inhibitors of the 11β-Hydroxysteroid Dehydrogenase Type 1

Tjeerd Barf, Jerk Vallgårda, Rikard Emond et al. · Journal of Medicinal Chemistry · 2002 · 211 citations · Full text

Pharmaceutical Science, Selective Inhibitors, Pharmacotherapy +20

Chemical Interrogation of FOXO3a Nuclear Translocation Identifies Potent and Selective Inhibitors of Phosphoinositide 3-Kinases

Wolfgang Link, Julen Oyarzábal, Beatriz G. Serelde et al. · Journal of Biological Chemistry · 2009 · 79 citations · Full text

Preclinical characterization of a potent and selective inhibitor of the histone demethylase KDM1A for MLL leukemia.

Tamara Maes, Iñigo Tirapu, Cristina Mascaró et al. · Journal of Clinical Oncology · 2013 · 38 citations

Histone Modifications, Mixed-phenotype Acute Leukemia, Epigenetic Change +24

Simultaneous inhibition of pan-phosphatidylinositol-3-kinases and MEK as a potential therapeutic strategy in peripheral T-cell lymphomas

Esperanza Martín‐Sánchez, Socorro Marıá Rodríguez-Pinilla, Margarita Sánchez‐Beato et al. · Haematologica · 2012 · 27 citations · Full text

Immunology, Cell Death, Immunotherapeutics +21