Loic Le Strat

Fragment Screening by Weak Affinity Chromatography: Comparison with Established Techniques for Screening against HSP90

Elinor Meiby, Heather Simmonite, Loic Le Strat et al. · Analytical Chemistry · 2013 · 59 citations

Hit Identification, Hsp90 Wac Columns, Fragment-based Lead Discovery +26

Application of Off-Rate Screening in the Identification of Novel Pan-Isoform Inhibitors of Pyruvate Dehydrogenase Kinase

Paul A. Brough, Lisa Baker, Simon T. Bedford et al. · Journal of Medicinal Chemistry · 2017 · 35 citations · Full text

Combining nucleoside analogues to achieve recognition of oligopurine tracts by triplex‐forming oligonucleotides at physiological pH

David A. Rusling, Loic Le Strat, Vicki E. C. Powers et al. · FEBS Letters · 2005 · 21 citations

A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase

Naoki Kuki, Lee Walmsley, Kazuo Kanai et al. · RSC Medicinal Chemistry · 2023 · 11 citations · Full text

Effects of a hairpin polyamide on DNA melting: comparison with distamycin and Hoechst 33258

Peter James, Loic Le Strat, Ulf Ellervik et al. · Biophysical Chemistry · 2004 · 10 citations

Dna Melting, Hoechst 33258, Hairpin Polyamide +8