A cancer-associated Epstein-Barr virus BZLF1 promoter variant enhances lytic infection

Jillian A. Bristol, Reza Djavadian, Emily R. Albright, +10

PLoS Pathogens

Lytic InfectionImmunologyPathologyImmunotherapyTumor Biology +14

Leflunomide/teriflunomide inhibit Epstein-Barr virus (EBV)-induced lymphoproliferative disease and lytic viral replication

Andrea Bilger, Julie Plowshay, Shidong Ma, +8

Oncotarget

Hsp90 Inhibitor 17-DMAG Decreases Expression of Conserved Herpesvirus Protein Kinases and Reduces Virus Production in Epstein-Barr Virus-Infected Cells

Xiaoping Sun, Jillian A. Bristol, Satoko Iwahori, +7

Journal of Virology

Latent Membrane Protein 1 (LMP1) and LMP2A Collaborate To Promote Epstein-Barr Virus-Induced B Cell Lymphomas in a Cord Blood-Humanized Mouse Model but Are Not Essential

Shi-Dong Ma, Ming‐Han Tsai, James C. Romero-Masters, +5

Journal of Virology

B cells infected with Type 2 Epstein-Barr virus (EBV) have increased NFATc1/NFATc2 activity and enhanced lytic gene expression in comparison to Type 1 EBV infection

James C. Romero-Masters, Shane M. Huebner, Makoto Ohashi, +13

PLoS Pathogens

Cancer-associated VirusEpstein-barr VirusPathogenesisViral PathogenesisImmunology +12

An EBNA3C-deleted Epstein-Barr virus (EBV) mutant causes B-cell lymphomas with delayed onset in a cord blood-humanized mouse model

James C. Romero-Masters, Makoto Ohashi, Reza Djavadian, +8

PLoS Pathogens

Ebv ProteinLymphoid NeoplasiaCancer-associated VirusHematologyImmunology +13

EBNA2-deleted Epstein-Barr virus (EBV) isolate, P3HR1, causes Hodgkin-like lymphomas and diffuse large B cell lymphomas with type II and Wp-restricted latency types in humanized mice

Chunrong Li, James C. Romero-Masters, Shane M. Huebner, +10

PLoS Pathogens

ImmunologyPathologyImmunotherapyType IiType Ii Latency +16

Hippo signaling effectors YAP and TAZ induce Epstein-Barr Virus (EBV) lytic reactivation through TEADs in epithelial cells

Nicholas Van Sciver, Makoto Ohashi, Nicholas P. Pauly, +4

PLoS Pathogens

Viral PathogenesisImmunologyPathologyImmunotherapyTumor Biology +16

CCAAT/enhancer binding proteins α and β regulate the tumor necrosis factor receptor 1 gene promoter

Jillian A. Bristol, Thomas E. Morrison, Shannon C. Kenney

Molecular Immunology

InflammationCytokineTranscriptional RegulationSignal TransductionSignaling Pathway +8

Epstein–Barr virus LMP1 protein promotes proliferation and inhibits differentiation of epithelial cells via activation of YAP and TAZ

Deo R. Singh, Scott E. Nelson, Abigail S. Pawelski, +6

Proceedings of the National Academy of Sciences