An inverse stage‐shift model to estimate the excess mortality and health economic impact of delayed access to cancer services due to the COVID‐19 pandemic

Koen Degeling, Nancy N. Baxter, Jon Emery, +7

Asia-Pacific Journal of Clinical Oncology

Towards Routine Implementation of Liquid Biopsies in Cancer Management: It Is Always Too Early, until Suddenly It Is Too Late

Maarten J. IJzerman, Jasper de Boer, Arun Azad, +10

Diagnostics

An inverse stage-shift model to estimate the excess mortality and health economic impact of delayed access to cancer services due to the COVID-19 pandemic

Koen Degeling, Nancy N. Baxter, Jon Emery, +6

Cancer ManagementPrognosisEpidemiology Of CancerCancer ServicesComputational Epidemiology +20

Accounting for parameter uncertainty in the definition of parametric distributions used to describe individual patient variation in health economic models

Koen Degeling, Maarten J. IJzerman, Miriam Koopman, +1

BMC Medical Research Methodology

Matching the model with the evidence: comparing discrete event simulation and state-transition modeling for time-to-event predictions in a cost-effectiveness analysis of treatment in metastatic colorectal cancer patients

Koen Degeling, Mira D. Franken, Anne M. May, +5

Cancer Epidemiology

Circulating Tumour DNA as a Potential Cost-Effective Biomarker to Reduce Adjuvant Chemotherapy Overtreatment in Stage II Colorectal Cancer

Yat Hang To, Koen Degeling, Suzanne Kosmider, +9

PharmacoEconomics

Surgical OncologyOncologyTumour DnaMedicineColorectal Cancer +7

Comparing Strategies for Modeling Competing Risks in Discrete-Event Simulations: A Simulation Study and Illustration in Colorectal Cancer

Koen Degeling, Hendrik Koffijberg, Mira D. Franken, +2

Medical Decision Making

Comparing Survival Outcomes for Advanced Cancer Patients Who Received Complex Genomic Profiling Using a Synthetic Control Arm

Sophie O’Haire, Koen Degeling, Fanny Franchini, +7

Targeted Oncology

Comparison of Timed Automata with Discrete Event Simulation for Modeling of Biomarker-Based Treatment Decisions: An Illustration for Metastatic Castration-Resistant Prostate Cancer

Koen Degeling, Stefano Schivo, Niven Mehra, +4

Value in Health

Stochastic SimulationUrologyEngineeringDiscrete Event SimulationDiscrete Modeling +9

Introduction to Metamodeling for Reducing Computational Burden of Advanced Analyses with Health Economic Models: A Structured Overview of Metamodeling Methods in a 6-Step Application Process

Koen Degeling, Maarten J. IJzerman, Mariel S. Lavieri, +2

Medical Decision Making