Martin J. Lear

Activity-Based Proteome Profiling of Potential Cellular Targets of Orlistat − An FDA-Approved Drug with Anti-Tumor Activities

Pengyu Yang, Kai Liu, Mun Hong Ngai et al. · Journal of the American Chemical Society · 2009 · 223 citations · Full text

Pharmacy, Biochemistry, Pharmacology +17

Lipidomic analysis of human tear fluid reveals structure-specific lipid alterations in dry eye syndrome

Sin Man Lam, Louis Tong, Bastien Reux et al. · Journal of Lipid Research · 2013 · 107 citations · Full text

Life Sciences, Biochemistry, Ophthalmology +17

Practical synthesis of maleimides and coumarin-linked probes for protein and antibody labelling via reduction of native disulfides

Hong Song, Mun Hong Ngai, Zhen Y. Song et al. · Organic & Biomolecular Chemistry · 2009 · 92 citations · Full text

Pharmacy, Biochemistry, Chemical Biology +15

A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases

Santosh R. Kotturi, Akhilesh Chong, Martin J. Lear et al. · Cell Death and Disease · 2010 · 87 citations · Full text

Life Sciences, Infectious Diseases, Pharmacology +17

A Direct and Efficientα-Selective Glycosylation Protocol for the Kedarcidin Sugar,L-Mycarose: AgPF6 as a Remarkable Activator of 2-Deoxythioglycosides

Martin J. Lear, Fumihiko Yoshimura, Masahiro Hirama · Angewandte Chemie International Edition · 2001 · 66 citations

Pharmacy, Biochemistry, Medicinal Chemistry +16