Ryan A. Frieler

Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice

Michael Usher, Sheng Zhong Duan, Christine Y. Ivaschenko et al. · Journal of Clinical Investigation · 2010 · 378 citations · Full text

Life Sciences, Cardiology, Physiology +16

Coxibs interfere with the action of aspirin by binding tightly to one monomer of cyclooxygenase-1

Gilad Rimon, Ranjinder S. Sidhu, Adam Lauver et al. · Proceedings of the National Academy of Sciences · 2009 · 202 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Neutrophils Restrict Tumor-Associated Microbiota to Reduce Growth and Invasion of Colon Tumors in Mice

Daniel Triner, Samantha N. Devenport, Sadeesh K. Ramakrishnan et al. · Gastroenterology · 2018 · 170 citations

Life Sciences, Immunology, Oncology +14

Myeloid-Specific Deletion of the Mineralocorticoid Receptor Reduces Infarct Volume and Alters Inflammation During Cerebral Ischemia

Ryan A. Frieler, He Meng, Sheng Zhong Duan et al. · Stroke · 2010 · 111 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Itaconate suppresses atherosclerosis by activating a Nrf2-dependent antiinflammatory response in macrophages in mice

Jianrui Song, Yanling Zhang, Ryan A. Frieler et al. · Journal of Clinical Investigation · 2023 · 78 citations · Full text

Life Sciences, Immunology, Pharmacology +17