Rajasekharan Somasundaram

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

Gang Chen, Alexander C. Huang, Wei Zhang et al. · Nature · 2018 · 2.8K citations · Full text

Life Sciences, Immunology, Oncology +14

Acquired Resistance to BRAF Inhibitors Mediated by a RAF Kinase Switch in Melanoma Can Be Overcome by Cotargeting MEK and IGF-1R/PI3K

Jessie Villanueva, Adina Vultur, John Tayu Lee et al. · Cancer Cell · 2010 · 1.2K citations · Full text

Medicine, Cancer Biology, Oncology +13

Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility

Amanpreet Kaur, Brett L. Ecker, Stephen M. Douglass et al. · Cancer Discovery · 2018 · 415 citations

Medicine, Immunology, Oncology +17

B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma

Johannes Griss, Wolfgang Bauer, Christine Wagner et al. · Nature Communications · 2019 · 380 citations · Full text

Life Sciences, Immunology, Oncology +17

Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations

Curtis H. Kugel, Stephen M. Douglass, Marie R. Webster et al. · Clinical Cancer Research · 2018 · 361 citations · Full text

Medicine, Immunology, Oncology +17