Xiwen Dai

Design, synthesis and biological evaluation of 1-alkyl-5/6-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-1H-indole-3-carbonitriles as novel xanthine oxidase inhibitors

Jun Gao, Xuegui Liu, Bing Zhang et al. · European Journal of Medicinal Chemistry · 2020 · 47 citations · Full text

Bioorganic Chemistry, Biochemistry, Medicine +8

Design, synthesis and biological evaluation of 2-(4-alkoxy-3-cyano)phenyl-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid derivatives as novel xanthine oxidase inhibitors

Qing Mao, Xiwen Dai, Gaoyang Xu et al. · European Journal of Medicinal Chemistry · 2019 · 41 citations · Full text

Medicinal Chemistry, Natural Product Synthesis, Bioorganic Chemistry +8

Targeting the subpocket in xanthine oxidase: Design, synthesis, and biological evaluation of 2-[4-alkoxy-3-(1H-tetrazol-1-yl) phenyl]-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid derivatives

Bing Zhang, Xiwen Dai, Ziyang Bao et al. · European Journal of Medicinal Chemistry · 2019 · 41 citations · Full text

Bioorganic Chemistry, Biochemistry, Natural Sciences +7

Novel 3-[4-alkoxy-3-(1H-tetrazol-1-yl) phenyl]-1,2,4-oxadiazol-5(4H)-ones as promising xanthine oxidase inhibitors: Design, synthesis and biological evaluation

Jun Gao, Zhaofeng Zhang, Bing Zhang et al. · Bioorganic Chemistry · 2019 · 32 citations

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +9

Design, synthesis, and biological evaluation of N-(3-cyano-1H-indol-5/6-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamides and 5-(6-oxo-1,6-dihydropyrimidin-2-yl)-1H-indole-3-carbonitriles as novel xanthine oxidase inhibitors

Bing Zhang, Yulin Duan, Yuwei Yang et al. · European Journal of Medicinal Chemistry · 2021 · 28 citations · Full text

Bioorganic Chemistry, Biochemistry, Medicine +8