Reto Eggenschwiler

Improved bi-allelic modification of a transcriptionally silent locus in patient-derived iPSC by Cas9 nickase

Reto Eggenschwiler, Mohsen Moslem, Mariane Fráguas-Eggenschwiler et al. · Scientific Reports · 2016 · 77 citations · Full text

Promoter and lineage independent anti-silencing activity of the A2 ubiquitous chromatin opening element for optimized human pluripotent stem cell-based gene therapy

Mania Ackermann, Nico Lachmann, Susann Hartung et al. · Biomaterials · 2013 · 64 citations

Chromatin, Induced Pluripotent Stem Cell, In Vivo Gene Therapy +10

Altered calcium dynamics and glutamate receptor properties in iPSC-derived motor neurons from ALS patients with C9orf72, FUS, SOD1 or TDP43 mutations

Franziska Bursch, Norman Kalmbach, Maximilian Naujock et al. · Human Molecular Genetics · 2019 · 54 citations

Sustained Knockdown of a Disease-Causing Gene in Patient-Specific Induced Pluripotent Stem Cells Using Lentiviral Vector-Based Gene Therapy

Reto Eggenschwiler, Komal Loya, Guangming Wu et al. · Stem Cells Translational Medicine · 2013 · 41 citations · Full text

A selectable all-in-one CRISPR prime editing piggyBac transposon allows for highly efficient gene editing in human cell lines

Reto Eggenschwiler, Thomas Gschwendtberger, Christian Felski et al. · Scientific Reports · 2021 · 31 citations · Full text