Karunakaran Kalesh

High-Throughput Discovery of <i>Mycobacterium tuberculosis</i> Protein Tyrosine Phosphatase B (MptpB) Inhibitors Using Click Chemistry

Lay Pheng Tan, Hao Wu, Pengyu Yang et al. · Organic Letters · 2009 · 68 citations

High-throughput synthesis of azide libraries suitable for direct “click” chemistry and in situ screening

Rajavel Srinivasan, Lay Pheng Tan, Hao Wu et al. · Organic & Biomolecular Chemistry · 2009 · 62 citations · Full text

Azide Libraries, Current Drug Discovery, Medicinal Chemistry +15

Peptide-based activity-based probes (ABPs) for target-specific profiling of proteintyrosine phosphatases (PTPs)

Karunakaran Kalesh, Lay Pheng Tan, Kai Lü et al. · Chemical Communications · 2009 · 55 citations · Full text

Proteinlipid Interaction, Peptide Engineering, Proteintyrosine Phosphatases +17

Methods of using click chemistry in the discovery of enzyme inhibitors

Rajavel Srinivasan, Junqi Li, Su Ling Ng et al. · Nature Protocols · 2007 · 49 citations

Medicinal Chemistry, Biochemistry, Natural Sciences +8

Rapid synthesis of Abelson tyrosine kinase inhibitors using click chemistry

Karunakaran Kalesh, Kai Liu, Shao Q. Yao · Organic & Biomolecular Chemistry · 2009 · 37 citations · Full text

Medicinal Chemistry, Chronic Myeloid Leukemia, Drug Target +14