Dennis W. Wolan

Proteome-wide covalent ligand discovery in native biological systems

Keriann M. Backus, Bruno E. Correia, Kenneth M. Lum et al. · Nature · 2016 · 936 citations

Biochemistry, Natural Sciences, Proteomics +3

METLIN: A Technology Platform for Identifying Knowns and Unknowns

Carlos Guijas, J. Rafael Montenegro-Burke, Xavier Domingo-Almenara et al. · Analytical Chemistry · 2018 · 926 citations · Full text

Engineering, Metabolomic Profiling, Molecular Biology +28

Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic

Emily N. Chin, Chenguang Yu, Vincent F. Vartabedian et al. · Science · 2020 · 483 citations

Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry

Seiya Kitamura, Qinheng Zheng, Jordan L. Woehl et al. · Journal of the American Chemical Society · 2020 · 199 citations · Full text

SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase

Qinheng Zheng, Jordan L. Woehl, Seiya Kitamura et al. · Proceedings of the National Academy of Sciences · 2019 · 188 citations · Full text