Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating Mutations

Rinath Jeselsohn, Johann S. Bergholz, Matthew Pun, +23

Cancer Cell

ChromatinGenome InstabilityAllele-specific Chromatin RecruitmentChromatin RemodelingGenetics +4

VIPER: Visualization Pipeline for RNA-seq, a Snakemake workflow for efficient and complete RNA-seq analysis

MacIntosh Cornwell, Mahesh Vangala, Len Taing, +12

BMC Bioinformatics

Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways

Sriram Venneti, Abed Rahman Kawakibi, Sunjong Ji, +81

Cancer Discovery

Embryonic transcription factor SOX9 drives breast cancer endocrine resistance

Rinath Jeselsohn, MacIntosh Cornwell, Matthew Pun, +20

Proceedings of the National Academy of Sciences

Lineage PlasticitySystems BiologyBreast OncologyTamoxifen ResistanceHormonal Receptor +10

Estrogen receptor signaling is reprogrammed during breast tumorigenesis

David Chi, Hari Singhal, Lewyn Li, +11

Proceedings of the National Academy of Sciences

Impact of a Pre-Operative Exercise Intervention on Breast Cancer Proliferation and Gene Expression: Results from the Pre-Operative Health and Body (PreHAB) Study

Jennifer A. Ligibel, Deborah Dillon, Anita Giobbie‐Hurder, +20

Clinical Cancer Research

Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas

Pooja Panwalkar, Benita Tamrazi, Derek Dang, +42

Science Translational Medicine

Unraveling the clinicopathological features driving the emergence of ESR1 mutations in metastatic breast cancer

Yanan Kuang, Bilal A. Siddiqui, Jiani Hu, +14

npj Breast Cancer

Epigenetically defined therapeutic targeting in H3.3G34R/V high-grade gliomas

Stefan R. Sweha, Chan Chung, Siva Kumar Natarajan, +27

Science Translational Medicine

Common molecular features of H3K27M DMGs and PFA ependymomas map to hindbrain developmental pathways

Matthew Pun, Drew Pratt, Patricia R. Nano, +11

Acta Neuropathologica Communications