Distinct and Dynamic ON and OFF Neural Ensembles in the Prefrontal Cortex Code Social Exploration

Bo Liang, Lifeng Zhang, Giovanni Barbera, +6

Neuron

Cognitive ScienceNeuropsychologyBrain FunctionBrain MechanismComputational Neuroscience +12

Metformin ameliorates stress-induced depression-like behaviors via enhancing the expression of BDNF by activating AMPK/CREB-mediated histone acetylation

Wenting Fang, Jing Zhang, Luyan Hong, +4

Journal of Affective Disorders

Stress-induced Depression-like BehaviorsStress HormonePsychiatryStressMedicine +8

Curcumin Ameliorates Memory Decline via Inhibiting BACE1 Expression and β-Amyloid Pathology in 5×FAD Transgenic Mice

Kun-Mu Zheng, Xiaoman Dai, Naian Xiao, +6

Molecular Neurobiology

Neurodegenerative Diseasesβ-Amyloid PathologyInhibiting Bace1 ExpressionMemoryDegenerative Pathology +8

Acetate supplementation produces antidepressant-like effect via enhanced histone acetylation

Weibin Huang, Wenming Hu, Lili Cai, +6

Journal of Affective Disorders

PsychiatryMedicinePsychopharmacologyDepressionPharmacology +1

ACSS2-dependent histone acetylation improves cognition in mouse model of Alzheimer’s disease

Yingbin Lin, Anlan Lin, Lili Cai, +12

Molecular Neurodegeneration

APOE4 genotype exacerbates the depression-like behavior of mice during aging through ATP decline

Wenting Fang, Naian Xiao, Guirong Zeng, +6

Translational Psychiatry

Metformin treatment improves the spatial memory of aged mice in an <i>APOE</i> genotype–dependent manner

Jing Zhang, Yingbin Lin, Xiaoman Dai, +3

The FASEB Journal

Ganoderma Lucidum Triterpenoids Improve Maternal Separation-Induced Anxiety- and Depression-like Behaviors in Mice by Mitigating Inflammation in the Periphery and Brain

Xue Mi, Guirong Zeng, Jie‐Qing Liu, +6

Nutrients

Affective NeuroscienceSocial SciencesStressNeuroimmunologyStress Biomarkers +15

Early-life stress leads to impaired spatial learning and memory in middle-aged ApoE4-TR mice

Lanyan Lin, Jing Zhang, Xiaoman Dai, +6

Molecular Neurodegeneration

LHPP in Glutamatergic Neurons of the Ventral Hippocampus Mediates Depression-like Behavior by Dephosphorylating CaMKIIα and ERK

Lv-Ping Zhuang, Weijie Gao, Yanbing Chen, +4

Biological Psychiatry

Synaptic PlasticityNeurobiological MechanismMolecular NeurosciencePsychiatryBehavioral Neuroscience +9