Concepedia

Simon Wheeler

SW

12

Publications

252

Citations

10

H-Index

2008

Active since

Affiliations

Pfizer (United Kingdom)(Current)

University of Leicester

De Montfort University

Loughborough University

Simon Wheeler is an author at Pfizer (United Kingdom) specializing in medicine, drug discovery, and pharmacotherapy.

Top concepts

MedicinePharmacologyDrug DiscoveryPharmacotherapyChemistryOrganic ChemistryMolecular PharmacologyCatalysisPathologyGynecology

Publications per year

2008–2022

12

Publications

12

Multiparameter Optimization in CNS Drug Discovery: Design of Pyrimido[4,5- <i>d</i> ]azepines as Potent 5-Hydroxytryptamine 2C (5-HT <sub>2C</sub> ) Receptor Agonists with Exquisite Functional Selectivity over 5-HT <sub>2A</sub> and 5-HT <sub>2B</sub> Receptors

Richard Storer, Paul E. Brennan, Alan D. Brown et al. · Journal of Medicinal Chemistry · 2014 · 37 citations · Full text

The Synthesis of Two Potent β-3 Adrenergic Receptor Agonists

Paul A. Bradley, Robert J. Carroll, Yann C. Lecouturier et al. · Organic Process Research & Development · 2010 · 30 citations

Asymmetric Catalysis, Molecular Pharmacology, Initial Preparation +14

Cytosolic glucosylceramide regulates endolysosomal function in Niemann-Pick type C disease

Simon Wheeler, Per Haberkant, Meenakshi Bhardwaj et al. · Neurobiology of Disease · 2019 · 29 citations · Full text

Autoimmune Disease, Disease Mechanism, Pathogenesis +8

Studies on the palladium-catalysed direct alkenylation of 1,2-azoles

Ben Chappell, Nathan Dedman, Simon Wheeler · Tetrahedron Letters · 2011 · 28 citations

Engineering, Palladium-catalysed Direct Alkenylation, Alkene Metathesis +4

Lipid–Protein Interactions in Niemann–Pick Type C Disease: Insights from Molecular Modeling

Simon Wheeler, Ralf Schmid, Daniel J. Sillence · International Journal of Molecular Sciences · 2019 · 25 citations · Full text

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