Simon Wheeler - Concepedia

Author

Simon Wheeler

Pfizer (United Kingdom)ORCID

Also Known As

S. Wheeler, Simon Wheeler, Wheeler, Simon

Publications

398

Citations

H-Index

Concepts

All Affiliations

Pfizer (United Kingdom)University of Leicester De Montfort University Loughborough University

About

Simon Wheeler is an author at Pfizer (United Kingdom) specializing in medicine, drug discovery, and pharmacotherapy.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	4	4	91
2	Chemistry	2	2	38
3	Engineering	1	1	28
4	Biochemistry	1	1	30
5	Cell Biology	1	1	29

Simon Wheeler

Publications

252

Citations

H-Index

Page 1

	Year	Citations
Multiparameter Optimization in CNS Drug Discovery: Design of Pyrimido[4,5- <i>d</i> ]azepines as Potent 5-Hydroxytryptamine 2C (5-HT <sub>2C</sub> ) Receptor Agonists with Exquisite Functional Selectivity over 5-HT <sub>2A</sub> and 5-HT <sub>2B</sub> Receptors Richard Storer, Paul E. Brennan, Alan D. Brown, Journal of Medicinal Chemistry	2014	37
The Synthesis of Two Potent β-3 Adrenergic Receptor Agonists Paul A. Bradley, Robert J. Carroll, Yann C. Lecouturier, Organic Process Research & Development Asymmetric CatalysisMolecular PharmacologyInitial PreparationBiochemistryMedicine	2010	30
Cytosolic glucosylceramide regulates endolysosomal function in Niemann-Pick type C disease Simon Wheeler, Per Haberkant, Meenakshi Bhardwaj, Neurobiology of Disease Autoimmune DiseaseDisease MechanismPathogenesisEndocytic PathwayPathology	2019	29
Studies on the palladium-catalysed direct alkenylation of 1,2-azoles Ben Chappell, Nathan Dedman, Simon Wheeler Tetrahedron Letters EngineeringPalladium-catalysed Direct AlkenylationAlkene MetathesisOrganic ChemistryOrganometallic Catalysis	2011	28
Lipid–Protein Interactions in Niemann–Pick Type C Disease: Insights from Molecular Modeling Simon Wheeler, Ralf Schmid, Daniel J. Sillence International Journal of Molecular Sciences	2019	25
Sterically demanding macrocyclic Eu(<scp>iii</scp>) complexes for selective recognition of phosphate and real-time monitoring of enzymatically generated adenosine monophosphate Samantha E. Bodman, Colum Breen, Sam Kirkland, Chemical Science	2022	23
Discovery of PF-184563, a potent and selective V1a antagonist for the treatment of dysmenorrhoea. The influence of compound flexibility on microsomal stability Patrick S. Johnson, Thomas Ryckmans, Justin S. Bryans, Bioorganic & Medicinal Chemistry Letters Compound FlexibilityMicrosomal StabilityMedicineGynecologyPharmacotherapy	2011	20
Linifanib – a multi-targeted receptor tyrosine kinase inhibitor and a low molecular weight gelator Maria Marlow, Mohammed Al-Ameedee, Thomas D. Smith, Chemical Communications	2015	15
Anion binding to a cationic europium( <scp>iii</scp> ) probe enables the first real-time assay of heparan sulfotransferase activity Simon Wheeler, Colum Breen, Yong Li, Organic & Biomolecular Chemistry	2021	13
Preparation of triazolobenzodiazepine derivatives as Vasopressin V1a antagonists David M. Beal, Justin S. Bryans, Patrick S. Johnson, Tetrahedron Letters Molecular PharmacologyMedicinal ChemistryTriazolobenzodiazepine DerivativesMedicinePharmacological Agent	2011	12

Page 1