Jean-Hugues Guervilly

The SLX4 Complex Is a SUMO E3 Ligase that Impacts on Replication Stress Outcome and Genome Stability

Jean-Hugues Guervilly, Arato Takedachi, Valeria Naim et al. · Molecular Cell · 2014 · 134 citations · Full text

Genome Stability, Genome Instability, Natural Sciences +9

SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance

Stephanie Panier, Marija Marić, Graeme Hewitt et al. · Molecular Cell · 2019 · 88 citations · Full text

SLX4 interacts with RTEL1 to prevent transcription-mediated DNA replication perturbations

Arato Takedachi, Emmanuelle Despras, Sarah Scaglione et al. · Nature Structural & Molecular Biology · 2020 · 72 citations · Full text

Transcriptional Regulation, Natural Sciences, Genetics +7

USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation

Jean-Hugues Guervilly, Emilie Renaud, Minoru Takata et al. · Human Molecular Genetics · 2011 · 65 citations · Full text

Molecular Biology, Cell Cycle, Signaling Pathway +17

Loss of CHK1 function impedes DNA damage-induced FANCD2 monoubiquitination but normalizes the abnormal G2 arrest in Fanconi anemia

Jean-Hugues Guervilly, Gaëtane Macé‐Aimé, Filippo Rosselli · Human Molecular Genetics · 2007 · 65 citations · Full text

Chromatin, Genome Instability, Fanconi Anemia +11