Tien M. Truong

Potent and Specific Inhibition of Human Leukocyte Elastase, Cathepsin G and Proteinase 3 by Sulfone Derivatives Employing the 1,2,5-Thiadiazolidin-3-one 1,1 Dioxide Scaffold

William C. Groutas, Rongze Kuang, Sumei Ruan et al. · Bioorganic & Medicinal Chemistry · 1998 · 71 citations

Life Sciences, Medicinal Chemistry, Pharmacology +11

Utilization of the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold in the design of potent inhibitors of serine proteases: SAR studies using carboxylates

Rongze Kuang, Jeffrey B. Epp, Sumei Ruan et al. · Bioorganic & Medicinal Chemistry · 2000 · 51 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Design, synthesis, and in vitro inhibitory activity toward human leukocyte elastase, cathepsin G, and proteinase 3 of saccharin-derived sulfones and congeners

William C. Groutas, Jeffrey B. Epp, R. Venkataraman et al. · Bioorganic & Medicinal Chemistry · 1996 · 39 citations

Life Sciences, Biochemistry, Medicinal Chemistry +7

Impact of <i>CYP2D6</i> Pharmacogenomic Status on Pain Control Among <scp>Opioid-Treated</scp> Oncology Patients

Natalie Reizine, Keith Danahey, Emily Schierer et al. · The Oncologist · 2021 · 29 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

US Food and Drug Administration Approval Summary: Talazoparib in Combination With Enzalutamide for Treatment of Patients With Homologous Recombination Repair Gene-Mutated Metastatic Castration-Resistant Prostate Cancer

Brian L. Heiss, Elaine Chang, Xin Gao et al. · Journal of Clinical Oncology · 2024 · 25 citations · Full text

Pharmacy, Oncology, Pharmacotherapy +17