Barry R. Hayter

Palladium‐Catalyzed Three‐Component Diaryl Sulfone Synthesis Exploiting the Sulfur Dioxide Surrogate DABSO

Edward J. Emmett, Barry R. Hayter, Michael C. Willis · Angewandte Chemie International Edition · 2013 · 247 citations · Full text

Chemical Engineering, Cross-coupling Reaction, Engineering +10

Palladium‐Catalyzed Synthesis of Ammonium Sulfinates from Aryl Halides and a Sulfur Dioxide Surrogate: A Gas‐ and Reductant‐Free Process

Edward J. Emmett, Barry R. Hayter, Michael C. Willis · Angewandte Chemie International Edition · 2014 · 201 citations · Full text

Aryl Halides, Chemical Engineering, Engineering +12

Optimization of a Novel Binding Motif to (<i>E</i>)-3-(3,5-Difluoro-4-((1<i>R</i>,3<i>R</i>)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1<i>H</i>-pyrido[3,4-<i>b</i>]indol-1-yl)phenyl)acrylic Acid (AZD9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist

Chris De Savi, Robert H. Bradbury, Alfred A. Rabow et al. · Journal of Medicinal Chemistry · 2015 · 159 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Positive Breast Cancer +18

Palladium-catalysed aminosulfonylation of aryl-, alkenyl- and heteroaryl halides: scope of the three-component synthesis of N-aminosulfonamides

Edward J. Emmett, Charlotte S. Richards‐Taylor, Bao N. Nguyen et al. · Organic & Biomolecular Chemistry · 2012 · 110 citations

Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II: Broad-Spectrum Antibacterial Agents with Reduced hERG Activity

Folkert Reck, Richard A. Alm, Patrick Brassil et al. · Journal of Medicinal Chemistry · 2011 · 101 citations · Full text

Reduced Herg Activity, Antimicrobial Chemotherapy, Pharmaceutical Chemistry +21