Ruitong Li

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers

Takahiro Ito, Michael J. Young, Ruitong Li et al. · Nature Genetics · 2021 · 171 citations

Medicine, Molecular Biology, Oncology +14

Molecular basis for substrate recruitment to the PRMT5 methylosome

Kathleen M. Mulvaney, Christa Blomquist, Nischal Acharya et al. · Molecular Cell · 2021 · 84 citations · Full text

Life Sciences, Genetics, Molecular Biology +6

Distinct CDK6 complexes determine tumor cell response to CDK4/6 inhibitors and degraders

Xuewei Wu, Xiaobao Yang, Yan Xiong et al. · Nature Cancer · 2021 · 72 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +9

5-HT<sub>2A</sub> Receptor and 5-HT Degradation Play a Crucial Role in Atherosclerosis by Modulating Macrophage Foam Cell Formation, Vascular Endothelial Cell Inflammation, and Hepatic Steatosis

Yingying Ma, Xiurui Liang, Chen Li et al. · Journal of Atherosclerosis and Thrombosis · 2021 · 45 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Systematic profiling of conditional pathway activation identifies context-dependent synthetic lethalities

Liang Chang, Nancy Yoobin Jung, Adel Atari et al. · Nature Genetics · 2023 · 43 citations

Life Sciences, Bioinformatics, Molecular Genetics +13