Amy Coon

Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity

Emmanuelle J. Meuillet, Daruka Mahadevan, Margareta Berggren et al. · Archives of Biochemistry and Biophysics · 2004 · 192 citations

Life Sciences, Biochemistry, Cell Biology +17

Specific inhibition of the Akt1 pleckstrin homology domain by D-3-deoxy-phosphatidyl-myo-inositol analogues.

Emmanuelle J. Meuillet, Daruka Mahadevan, Hariprasad Vankayalapati et al. · PubMed · 2003 · 78 citations

Life Sciences, Cell Biology, Molecular Biology +15

Mitomycin C Inhibits Ribosomal RNA

Ryan G. Snodgrass, Abby C. Collier, Amy Coon et al. · Journal of Biological Chemistry · 2010 · 67 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

In Vivo Molecular Pharmacology and Antitumor Activity of the Targeted Akt Inhibitor PX-316

Emmanuelle J. Meuillet, Nathan T. Ihle, Amanda F. Baker et al. · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics · 2004 · 52 citations · Full text

Medicine, Pharmacology, Molecular Pharmacology +9

Antitumor agent PX-12 inhibits HIF-1α protein levels through an Nrf2/PMF-1-mediated increase in spermidine/spermine acetyl transferase

Yon Hui Kim, Amy Coon, Amanda F. Baker et al. · Cancer Chemotherapy and Pharmacology · 2010 · 44 citations

Medicine, Oncology, Pharmacology +7