Melanie Radloff

Active site rearrangement and structural divergence in prokaryotic respiratory oxidases

Schara Safarian, Alexander Hahn, Deryck J. Mills et al. · Science · 2019 · 132 citations

Life Sciences, Biochemistry, Microbiology +17

The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB

Schara Safarian, Helen K. Opel‐Reading, Di Wu et al. · Nature Communications · 2021 · 68 citations · Full text

Life Sciences, Biochemistry, Biology +17

Mechanistic and structural diversity between cytochrome <i>bd</i> isoforms of <i>Escherichia coli</i>

Tamara N. Grund, Melanie Radloff, Di Wu et al. · Proceedings of the National Academy of Sciences · 2021 · 34 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Short-chain aurachin D derivatives are selective inhibitors of E. coli cytochrome bd-I and bd-II oxidases

Melanie Radloff, Isam Elamri, Tamara N. Grund et al. · Scientific Reports · 2021 · 19 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +14

Ligand binding and conformational dynamics of the <i>E. coli</i> nicotinamide nucleotide transhydrogenase revealed by hydrogen/deuterium exchange mass spectrometry

Jonathan Zöller, Sangjin Hong, Martin Eisinger et al. · Computational and Structural Biotechnology Journal · 2022 · 10 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17