Tatsuhito Uno

A Rapamycin-Sensitive Pathway Down-Regulates Insulin Signaling via Phosphorylation and Proteasomal Degradation of Insulin Receptor Substrate-1

Tetsuro Haruta, Tatsuhito Uno, Junko Kawahara et al. · Molecular Endocrinology · 2000 · 412 citations

Mammalian Target of Rapamycin Pathway Regulates Insulin Signaling via Subcellular Redistribution of Insulin Receptor Substrate 1 and Integrates Nutritional Signals and Metabolic Signals of Insulin

Atsuko Takano, Isao Usui, Tetsuro Haruta et al. · Molecular and Cellular Biology · 2001 · 250 citations · Full text

Metabolic Remodeling, Subcellular Redistribution, Insulin Signaling +22

Pioglitazone Ameliorates Tumor Necrosis Factor-α–Induced Insulin Resistance by a Mechanism Independent of Adipogenic Activity of Peroxisome Proliferator–Activated Receptor-γ

Minoru Iwata, Tetsuro Haruta, Isao Usui et al. · Diabetes · 2001 · 110 citations · Full text

Growth Hormone Induces Cellular Insulin Resistance by Uncoupling Phosphatidylinositol 3-Kinase and Its Downstream Signals in 3T3-L1 Adipocytes

Atsuko Takano, Tetsuro Haruta, Minoru Iwata et al. · Diabetes · 2001 · 109 citations · Full text

Retinoblastoma Protein Phosphorylation via PI 3-Kinase and mTOR Pathway Regulates Adipocyte Differentiation

Isao Usui, Tetsuro Haruta, Minoru Iwata et al. · Biochemical and Biophysical Research Communications · 2000 · 27 citations

Signal Transduction, Signaling Pathway, Cell Regulation +10