Wolfgang W. Wicha

Efficacy and Safety of Intravenous-to-oral Lefamulin, a Pleuromutilin Antibiotic, for the Treatment of Community-acquired Bacterial Pneumonia: The Phase III Lefamulin Evaluation Against Pneumonia (LEAP 1) Trial

Thomas M. File, Lisa Goldberg, Anita Das et al. · Clinical Infectious Diseases · 2019 · 142 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +14

Oral Lefamulin vs Moxifloxacin for Early Clinical Response Among Adults With Community-Acquired Bacterial Pneumonia

Elizabeth Alexander, Lisa Goldberg, Anita Das et al. · JAMA · 2019 · 108 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +15

Pharmacokinetics/pharmacodynamics of lefamulin in a neutropenic murine pneumonia model with<i>Staphylococcus aureus</i>and<i>Streptococcus pneumoniae</i>

Wolfgang W. Wicha, Dirk B Strickmann, Susanne Paukner · Journal of Antimicrobial Chemotherapy · 2019 · 39 citations · Full text

Medicine, Infectious Diseases, Pharmacology +16

Population Pharmacokinetic Analyses for BC-3781 Using Phase 2 Data from Patients with Acute Bacterial Skin and Skin Structure Infections

Christopher M. Rubino, Sujata M. Bhavnani, William Prince et al. · Antimicrobial Agents and Chemotherapy · 2014 · 30 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

<i>In vivo</i>pharmacodynamics of lefamulin, the first systemic pleuromutilin for human use, in a neutropenic murine thigh infection model

Wolfgang W. Wicha, William A. Craig, David R. Andes · Journal of Antimicrobial Chemotherapy · 2019 · 29 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +14