Dominic J. Gessler

Global CNS Transduction of Adult Mice by Intravenously Delivered rAAVrh.8 and rAAVrh.10 and Nonhuman Primates by rAAVrh.10

Bin Yang, Shaoyong Li, Hongyan Wang et al. · Molecular Therapy · 2014 · 204 citations · Full text

A Rationally Engineered Capsid Variant of AAV9 for Systemic CNS-Directed and Peripheral Tissue-Detargeted Gene Delivery in Neonates

Dan Wang, Shaoyong Li, Dominic J. Gessler et al. · Molecular Therapy — Methods & Clinical Development · 2018 · 75 citations · Full text

Redirecting N-acetylaspartate metabolism in the central nervous system normalizes myelination and rescues Canavan disease

Dominic J. Gessler, Danning Li, Hongxia Xu et al. · JCI Insight · 2017 · 66 citations · Full text

Structural characterization of a novel human adeno-associated virus capsid with neurotropic properties

Hung-Lun Hsu, Alexander Brown, A.B. Loveland et al. · Nature Communications · 2020 · 54 citations · Full text

Intravenous Infusion of AAV for Widespread Gene Delivery to the Nervous System

Dominic J. Gessler, Phillip W.L. Tai, Jia Li et al. · Methods in molecular biology · 2019 · 46 citations · Full text

Intravenous Infusion, Translational Medicine, In Vivo Gene Therapy +7