Mingguang Mo

Sphingomyelin synthase 2 facilitates M2-like macrophage polarization and tumor progression in a mouse model of triple-negative breast cancer

Yan Deng, Jia-chun Hu, Shuhua He et al. · Acta Pharmacologica Sinica · 2020 · 49 citations · Full text

Cancer Research, Breast Oncology, Medicine +10

Discovery of a Novel Series of Imidazo[1,2-<i>a</i>]pyrimidine Derivatives as Potent and Orally Bioavailable Lipoprotein-Associated Phospholipase A₂ Inhibitors

Xinde Chen, Wenwei Xu, Kai Wang et al. · Journal of Medicinal Chemistry · 2015 · 41 citations · Full text

Lipoprotein-associated Phospholipase A2, Molecular Pharmacology, Medicinal Chemistry +14

Discovery, synthesis and anti-atherosclerotic activities of a novel selective sphingomyelin synthase 2 inhibitor

Yali Li, Taomin Huang, Bin Lou et al. · European Journal of Medicinal Chemistry · 2018 · 28 citations · Full text

Biochemistry, Medicine, Natural Sciences +5

Discovery of 4-Benzyloxybenzo[<i>d</i>]isoxazole-3-amine Derivatives as Highly Selective and Orally Efficacious Human Sphingomyelin Synthase 2 Inhibitors that Reduce Chronic Inflammation in <i>db</i>/<i>db</i> Mice

Mingguang Mo, Jintong Yang, Xian‐Cheng Jiang et al. · Journal of Medicinal Chemistry · 2018 · 26 citations · Full text

Immunology, Pharmacotherapy, Pharmaceutical Chemistry +17

Site-Selective Phosphoglycerate Mutase 1 Acetylation by a Small Molecule

Xiaodan Zhang, Lulu Jiang, Ke Huang et al. · ACS Chemical Biology · 2020 · 20 citations