Danielle J. Blackwell

PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity

Joseph M. Gozgit, Melissa M. Vasbinder, Ryan Abo et al. · Cancer Cell · 2021 · 171 citations

Cytokine, Cancer Immunosurveillance, Medicine +9

A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants

Laurie B. Schenkel, Jennifer R. Molina, Kerren K. Swinger et al. · Cell chemical biology · 2021 · 71 citations · Full text

Inflammation, Selective Parp14 Inhibitor, Inflammatory Responses +10

Enabling drug discovery for the PARP protein family through the detection of mono-ADP-ribosylation

Alvin Lu, Ryan Abo, Yue Ren et al. · Biochemical Pharmacology · 2019 · 52 citations · Full text

Drug Target, Structural Bioinformatics, Biomolecular Structure Prediction +20

In Vitro and Cellular Probes to Study PARP Enzyme Target Engagement

Tim J. Wigle, Danielle J. Blackwell, Laurie B. Schenkel et al. · Cell chemical biology · 2020 · 24 citations · Full text

Signal Transduction, Protein Expression, Biochemistry +10

Targeted Degradation of PARP14 Using a Heterobifunctional Small Molecule

Tim J. Wigle, Yue Ren, Jennifer R. Molina et al. · ChemBioChem · 2021 · 23 citations