Virginie Floch

Cation Substitution in Cationic Phosphonolipids:  A New Concept To Improve Transfection Activity and Decrease Cellular Toxicity

Virginie Floch, Séverine Loisel, Erwann Guénin et al. · Journal of Medicinal Chemistry · 2000 · 122 citations

Pharmacy, Biochemistry, Biotechnology +17

Cationic Phosphonolipids Containing Quaternary Phosphonium and Arsonium Groups for DNA Transfection with Good Efficiency and Low Cellular Toxicity**

Erwann Guénin, Anne-Cécile Hervé, Virginie Floch et al. · Angewandte Chemie International Edition · 2000 · 100 citations

Pharmacy, Biotechnology, Molecular Pharmaceutics +10

Contribution of Plasmid DNA to Hepatotoxicity after Systemic Administration of Lipoplexes

Séverine Loisel, C. Gall, Laurent Doucet et al. · Human Gene Therapy · 2001 · 97 citations

Pharmacy, Pharmacology, Toxicology +17

Cationic Phosphonolipids as non Viral Vectors for DNA Transfection in Hematopoietic Cell Lines and CD34+ Cells

Virginie Floch, G Le Bolc'h, Marie‐Pierre Audrézet et al. · Blood Cells Molecules and Diseases · 1997 · 47 citations

Life Sciences, Cell Biology, Molecular Biology +13

Systemic administration of cationic phosphonolipids/DNA complexes and the relationship between formulation and lung transfection efficiency

Virginie Floch, Pascal Delépine, C. Guillaume et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 2000 · 37 citations

Pharmacy, Pharmaceutics, Pharmacology +15