Tracy L. Hutchison

BCX-1812 (RWJ-270201):  Discovery of a Novel, Highly Potent, Orally Active, and Selective Influenza Neuraminidase Inhibitor through Structure-Based Drug Design

Y.S. Babu, Pooran Chand, Shanta Bantia et al. · Journal of Medicinal Chemistry · 2000 · 376 citations · Full text

Crystal Structure, Medicinal Chemistry, Antimicrobial Drug Discovery +15

Systematic Structure-Based Design and Stereoselective Synthesis of Novel Multisubstituted Cyclopentane Derivatives with Potent Antiinfluenza Activity

Pooran Chand, Pravin L. Kotian, Ali Dehghani et al. · Journal of Medicinal Chemistry · 2001 · 174 citations · Full text

Screen Mixtures, Organic Chemistry, Chemistry +17

Comparison of the Anti-Influenza Virus Activity of RWJ-270201 with Those of Oseltamivir and Zanamivir

Shanta Bantia, Cynthia Parker, Sandya L. Ananth et al. · Antimicrobial Agents and Chemotherapy · 2001 · 148 citations · Full text

Medicinal Chemistry, Drug Discovery, Influenza Virus Neuraminidase +15

Addition of Lithiated 9-Deazapurine Derivatives to a Carbohydrate Cyclic Imine:  Convergent Synthesis of the Aza-<i>C</i>-nucleoside Immucillins

Gary B. Evans, Richard H. Furneaux, Tracy L. Hutchison et al. · The Journal of Organic Chemistry · 2001 · 90 citations

9-Deaza-9-lithiopurine Derivatives, Enantioselective Synthesis, Bioorganic Chemistry +13

Purine nucleoside phosphorylase inhibitor BCX-1777 (Immucillin-H)—a novel potent and orally active immunosuppressive agent

Shanta Bantia, Patrick J. Miller, Cynthia Parker et al. · International Immunopharmacology · 2001 · 88 citations

Active Immunosuppressive Agent, Medicine, Immunosuppressive Therapy +7