Gary F. Breen

The Development of a Manufacturing Route for the GPIIb/IIIa Receptor Antagonist SB-214857-A. Part 2:  Conversion of the Key Intermediate SB-235349 to SB-214857-A

Richard J. Atkins, Adam Banks, Richard K. Bellingham et al. · Organic Process Research & Development · 2003 · 49 citations

Enzymatic resolution of a secondary amine using novel acylating reagents

Gary F. Breen · Tetrahedron Asymmetry · 2004 · 47 citations

Biochemistry, Natural Sciences, Biocatalysis +5

A new synthesis of the GPIIb/IIIa receptor antagonist SB-214857-A

Ian P. Andrews, Richard J. Atkins, Neil F. Badham et al. · Tetrahedron Letters · 2001 · 29 citations

Molecular Pharmacology, G Protein-coupled Receptor, Medicine +6

Synthetic Routes to Quinoline Derivatives:  Novel Syntheses of 3-Butyryl-8-methoxy-4-[(2-methylphenyl)amino]quinoline and 3-Butyryl-8-(2-hydroxyethoxy)-4-[(2-methylphenyl)amino]quinoline

Richard J. Atkins, Gary F. Breen, Lynne P. Crawford et al. · Organic Process Research & Development · 1997 · 29 citations

Different Disconnection, Key Step, Engineering +15

Process Development and Scale Up of a Glycine Antagonist

Adam Banks, Gary F. Breen, Darren Caine et al. · Organic Process Research & Development · 2009 · 27 citations

Glycine Antagonist, Engineering, Medicine +11