Kevin S. Blake

Metagenomic Insight into Microbiome and Antibiotic Resistance Genes of High Clinical Concern in Urban and Rural Hospital Wastewater of Northern India Origin: a Major Reservoir of Antimicrobial Resistance

Absar Talat, Kevin S. Blake, Gautam Dantas et al. · Microbiology Spectrum · 2023 · 61 citations · Full text

Life Sciences, Microbiology, Antimicrobial Resistance +16

The tetracycline resistome is shaped by selection for specific resistance mechanisms by each antibiotic generation

Kevin S. Blake, Yao-Peng Xue, Vincent J. Gillespie et al. · Nature Communications · 2025 · 53 citations · Full text

Life Sciences, Evolutionary Biology, Microbiology +17

Impact of international travel and diarrhea on gut microbiome and resistome dynamics

Manish Boolchandani, Kevin S. Blake, Drake H. Tilley et al. · Nature Communications · 2022 · 48 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17

Structure-Based Design of Bisubstrate Tetracycline Destructase Inhibitors That Block Flavin Redox Cycling

Emily E. Williford, Caitlin M. DeAngelo, Kevin S. Blake et al. · Journal of Medicinal Chemistry · 2023 · 14 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases

Hirdesh Kumar, Emily E. Williford, Kevin S. Blake et al. · Communications Biology · 2023 · 14 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +16