James N.C. Kew

Ro 25–6981, a Highly Potent and Selective Blocker of N-Methyl-d-aspartate Receptors Containing the NR2B Subunit. Characterization in Vitro

G. Fischer, Vincent Mutel, Gerhard Trube et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 484 citations

Life Sciences, Neuroscience, Pharmacology +17

A novel mechanism of activity‐dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones.

James N.C. Kew, Gerhard Trube, John A. Kemp · The Journal of Physiology · 1996 · 239 citations

Life Sciences, Neuroscience, Pharmacology +17

Positive allosteric modulators of metabotropic glutamate 1 receptor: Characterization, mechanism of action, and binding site

Frédéric Knoflach, Vincent Mutel, Synèse Jolidon et al. · Proceedings of the National Academy of Sciences · 2001 · 236 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Developmental Changes in NMDA Receptor Glycine Affinity and Ifenprodil Sensitivity Reveal Three Distinct Populations of NMDA Receptors in Individual Rat Cortical Neurons

James N.C. Kew, J. G. Richards, Vincent Mutel et al. · Journal of Neuroscience · 1998 · 224 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

PS2APP Transgenic Mice, Coexpressing hPS2mut and hAPPswe, Show Age-Related Cognitive Deficits Associated with Discrete Brain Amyloid Deposition and Inflammation

John Richards, Guy A. Higgins, Abdel‐Mouttalib Ouagazzal et al. · Journal of Neuroscience · 2003 · 202 citations · Full text

Life Sciences, Neurology, Neuroscience +17