Association of the Autoimmune Disease Scleroderma with an Immunologic Response to Cancer

Christine Joseph, Erika Darrah, Ami A. Shah, +12

Science

Foreign AntigensScleroderma PatientsImmunologyPathologyDermatology +17

Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease−Associated Colorectal Cancers

Ana I. Robles, Giovanni Traverso, Ming Zhang, +13

Gastroenterology

Gastrointestinal OncologyMedicineWhole-exome Sequencing AnalysesGastroenterologyPathology +5

Exomic analysis of myxoid liposarcomas, synovial sarcomas, and osteosarcomas

Christine Joseph, Heejung Hwang, Yuchen Jiao, +12

Genes Chromosomes and Cancer

Identification of Putative Agouti-Related Protein(87−132)-Melanocortin-4 Receptor Interactions by Homology Molecular Modeling and Validation Using Chimeric Peptide Ligands

Andrzej Wilczyński, Xiang S. Wang, Christine Joseph, +8

Journal of Medicinal Chemistry

The 1,4-Benzodiazepine-2,5-dione Small Molecule Template Results in Melanocortin Receptor Agonists with Nanomolar Potencies

Christine Joseph, Krista R. Wilson, Michael S. Wood, +5

Journal of Medicinal Chemistry

γ2-Melanocyte stimulation hormone (γ2-MSH) truncation studies results in the cautionary note that γ2-MSH is not selective for the mouse MC3R over the mouse MC5R

Christine Joseph, Hua Yao, Joseph W. Scott, +4

Peptides

Signal TransductionMolecular PhysiologyMouse Mc5rEndocrine ResearchCell Signaling +8

Disrupted PI3K subunit p110α signaling protects against pulmonary hypertension and reverses established disease in rodents

Eva Berghausen, Wiebke Janssen, Marius Vantler, +16

Journal of Clinical Investigation

Inflammatory Lung DiseaseLung InflammationCell DeathPulmonary HypertensionMolecular Pharmacology +20

Urea small molecule agonists on mouse melanocortin receptors

Christine Joseph, Rayna M. Bauzo, Zhimin Xiang, +1

Bioorganic & Medicinal Chemistry Letters

Mouse Melanocortin ReceptorsG Protein-coupled ReceptorMedicineFunctional SelectivityReceptor (Biochemistry) +3

Elongation studies of the human agouti-related protein (AGRP) core decapeptide (Yc[CRFFNAFC]Y) results in antagonism at the mouse melanocortin-3 receptor

Christine Joseph, Rayna M. Bauzo, Zhimin Xiang, +3

Peptides

Core DecapeptideProtein FunctionSignal TransductionG Protein-coupled ReceptorMedicine +6

Chimeric NDP-MSH and MTII melanocortin peptides with agouti-related protein (AGRP) Arg-Phe-Phe amino acids possess agonist melanocortin receptor activity

Christine Joseph, Andrzej Wilczyński, Jerry Ryan Holder, +4

Peptides

Mtii MelanocortinSignal TransductionG Protein-coupled ReceptorMedicinePeptide Library +8