Concepedia

David D. Holcomb

DD

9

Publications

493

Citations

9

H-Index

2019

Active since

Affiliations

Center for Biologics Evaluation and Research(Current)

Cleveland State University

University of Connecticut

National Institutes of Health

National Center for Biotechnology Information

David D. Holcomb is an author at Center for Biologics Evaluation and Research specializing in medicine, genetics, and systems biology.

ORCID

Top concepts

Publications per year

2019–2022

9

Publications

9

Codon and Codon-Pair Usage Tables (CoCoPUTs): Facilitating Genetic Variation Analyses and Recombinant Gene Design

Aikaterini Alexaki, Jacob Kames, David D. Holcomb et al. · Journal of Molecular Biology · 2019 · 171 citations · Full text

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TissueCoCoPUTs: Novel Human Tissue-Specific Codon and Codon-Pair Usage Tables Based on Differential Tissue Gene Expression

Jacob Kames, Aikaterini Alexaki, David D. Holcomb et al. · Journal of Molecular Biology · 2020 · 79 citations

, , +12

Effects of codon optimization on coagulation factor IX translation and structure: Implications for protein and gene therapies

Aikaterini Alexaki, Gaya Hettiarachchi, John C. Athey et al. · Scientific Reports · 2019 · 72 citations · Full text

Sequence analysis of SARS-CoV-2 genome reveals features important for vaccine design

Jacob Kames, David D. Holcomb, Ofer Kimchi et al. · Scientific Reports · 2020 · 67 citations · Full text

A Single Synonymous Variant (c.354G>A [p.P118P]) in ADAMTS13 Confers Enhanced Specific Activity

Ryan Hunt, Gaya Hettiarachchi, Upendra Katneni et al. · International Journal of Molecular Sciences · 2019 · 27 citations · Full text

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