7-hydroxycoumarin modulates Nrf2/HO-1 and microRNA-34a/SIRT1 signaling and prevents cisplatin-induced oxidative stress, inflammation, and kidney injury in rats

Demiana H. Sami, Ayman S. Soliman, Akef A. Khowailed, +3

Life Sciences

InflammationRedox SignalingAnti-inflammatoryMicrorna-34a/sirt1 Signaling7-Hydroxycoumarin Modulates +9

Umbelliferone ameliorates ulcerative colitis induced by acetic acid via modulation of TLR4/NF-κB-p65/iNOS and SIRT1/PPARγ signaling pathways in rats

Basel A. Abdel‐Wahab, Saad A. Alkahtani, Abdulsalam A. Alqahtani, +1

Environmental Science and Pollution Research

InflammationChronic Inflammatory DiseasesAnti-inflammatoryMucosal ImmunologyMedicine +11

The antimicrobial, antibiofilm, and wound healing properties of ethyl acetate crude extract of an endophytic fungus Paecilomyces sp. (AUMC 15510) in earthworm model

Shimaa H. Salem, S. S. Mohamed El-Maraghy, A. Y. Abdel‐Mallek, +4

Scientific Reports

Candesartan Attenuates Cisplatin-Induced Lung Injury by Modulating Oxidative Stress, Inflammation, and TLR-4/NF-κB, JAK1/STAT3, and Nrf2/HO-1 Signaling

Ahmed M. Atwa, Omnia A. M. Abd El‐Ghafar, Emad H. M. Hassanein, +6

Pharmaceuticals

Acute Lung InjuryInflammatory Lung DiseaseChemoprevention StrategyLung InflammationLipid Peroxidation +18

Apocynin abrogates methotrexate-induced nephrotoxicity: role of TLR4/NF-κB-p65/p38-MAPK, IL-6/STAT-3, PPAR-γ, and SIRT1/FOXO3 signaling pathways

Emad H. M. Hassanein, Ahmed M. Sayed, Omnia A. M. Abd El‐Ghafar, +7

Archives of Pharmacal Research

InflammationRedox SignalingAnti-inflammatoryMedicineApoptosis +10

Role of NF-κB/ICAM-1, JAK/STAT-3, and apoptosis signaling in the anticancer effect of tangeretin against urethane-induced lung cancer in BALB/c mice

Maha M. Abdel‐Fattah, Wafaa R. Mohamed, Emad H. M. Hassanein, +2

Life Sciences

OncologyUrethane-induced Lung CancerLung InflammationMedicinePharmacology +9

Edaravone alleviates methotrexate-induced testicular injury in rats: Implications on inflammation, steroidogenesis, and Akt/p53 signaling

Emad H. M. Hassanein, Wafaa R. Mohamed, Rasha Hussein, +1

International Immunopharmacology

InflammationMethotrexate-induced Testicular InjuryMedicineImmunologyCell Death +4

Mechanism and impact of heavy metal-aluminum (Al) toxicity on male reproduction: Therapeutic approaches with some phytochemicals

Fares E.M. Ali, Khalid S.A. Badran, Hanan S. Althagafy, +1

Life Sciences

FertilityBioactive MetalToxicologyMetal ToxicityEnvironmental Toxicology +4

Neuroprotective effect of canagliflozin against cisplatin-induced cerebral cortex injury is mediated by regulation of HO-1/PPAR-γ, SIRT1/FOXO-3, JNK/AP-1, TLR4/iNOS, and Ang II/Ang 1–7 signals

Emad H. M. Hassanein, Fayez M. Saleh, Fares E.M. Ali, +3

Immunopharmacology and Immunotoxicology

Flavonoids of Haloxylon salicornicum (Rimth) prevent cisplatin-induced acute kidney injury by modulating oxidative stress, inflammation, Nrf2, and SIRT1

Shaymaa A. Ramadan, Emadeldin M. Kamel, Madeha A. Ewais, +3

Environmental Science and Pollution Research

InflammationPharmacologyPhytochemicalReactive Oxygen SpecieHaloxylon Salicornicum +3