Jan Gerard Maring

Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene.

André B. P. Kuilenburg, Janet Haasjes, Dick J. Richel et al. · PubMed · 2000 · 360 citations

Life Sciences, Biochemistry, Pharmacology +14

Intragenic deletions and a deep intronic mutation affecting pre-mRNA splicing in the dihydropyrimidine dehydrogenase gene as novel mechanisms causing 5-fluorouracil toxicity

André B. P. Kuilenburg, Judith Meijer, Adri N. Mul et al. · Human Genetics · 2010 · 113 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Reduced 5-FU clearance in a patient with low DPD activity due to heterozygosity for a mutant allele of the DPYD gene

Jan Gerard Maring, André B. P. Kuilenburg, Janet Haasjes et al. · British Journal of Cancer · 2002 · 99 citations · Full text

Medicine, Oncology, Pharmacology +17

A study of medication reviews to identify drug-related problems of polypharmacy patients in the Dutch nursing home setting

F. Finkers, Jan Gerard Maring, Froukje Boersma et al. · Journal of Clinical Pharmacy and Therapeutics · 2007 · 97 citations

Pharmacy, Clinical Pharmacy, Hospital Pharmacy +12

Evaluation of 5-Fluorouracil Pharmacokinetics in Cancer Patients with a C.1905+1G>A Mutation in DPYD by Means of a Bayesian Limited Sampling Strategy

André B. P. Kuilenburg, Peter Häusler, Andreas Schalhorn et al. · Clinical Pharmacokinetics · 2012 · 82 citations

Pharmacy, Oncology, Pharmacokinetics +13