O Hanscombe

Importance of globin gene order for correct developmental expression.

O Hanscombe, David Whyatt, Peter Fraser et al. · Genes & Development · 1991 · 294 citations · Full text

Transcriptional Regulation, Systems Biology, Developmental Biology +15

The β-globin dominant control region activates homologous and heterologous promoters in a tissue-specific manner

Greet Blom van Assendelft, O Hanscombe, F. Grosveld et al. · Cell · 1989 · 292 citations · Full text

Transcriptional Regulation, Signal Transduction, Protein Expression +11

Hypersensitive site 4 of the human β globin locus control region

Sara Pruzina, O Hanscombe, David Whyatt et al. · Nucleic Acids Research · 1991 · 136 citations · Full text

Chromatin, Hypersensitive Site 4, Signal Transduction +15

High-level, erythroid-specific expression of the human alpha-globin gene in transgenic mice and the production of human hemoglobin in murine erythrocytes.

O Hanscombe, Miguel Vidal, Jaspal Kaeda et al. · Genes & Development · 1989 · 79 citations · Full text

Beta-globin Dcr, Developmental Biology, Xenotransplantation +14

A single serine residue at position 375 of VP16 is critical for complex assembly with Oct-1 and HCF and is a target of phosphorylation by casein kinase II

Dawn O’Reilly, O Hanscombe, Peter O’Hare · The EMBO Journal · 1997 · 45 citations · Full text

Protein Chemistry, Position 375, Single Serine Residue +10