Yun Leng

Overexpression of microRNA-29b induces apoptosis of multiple myeloma cells through down regulating Mcl-1

Yikun Zhang, Hua Wang, Yun Leng et al. · Biochemical and Biophysical Research Communications · 2011 · 104 citations

Tumor Biology, Medicine, Cell Death +8

A Bim-targeting strategy overcomes adaptive bortezomib resistance in myeloma through a novel link between autophagy and apoptosis

Shuang Chen, Yu Zhang, Liang Zhou et al. · Blood · 2014 · 99 citations · Full text

Targeting SQSTM1/p62 Induces Cargo Loading Failure and Converts Autophagy to Apoptosis via NBK/Bik

Shuang Chen, Liang Zhou, Yu Zhang et al. · Molecular and Cellular Biology · 2014 · 93 citations · Full text

Mitophagy, Apoptosis, Cell Death +18

A regimen combining the Wee1 inhibitor AZD1775 with HDAC inhibitors targets human acute myeloid leukemia cells harboring various genetic mutations

Liang Zhou, Yuesheng Zhang, Shucheng Chen et al. · Leukemia · 2014 · 77 citations · Full text

Hematological Malignancy, Wee1 Inhibitor Azd1775, Medicine +8

The NAE inhibitor pevonedistat interacts with the HDAC inhibitor belinostat to target AML cells by disrupting the DDR

Liang Zhou, Shuang Chen, Yu Zhang et al. · Blood · 2016 · 58 citations · Full text