Karl M Gogan

Lactate Alters Metabolism in Human Macrophages and Improves Their Ability to Kill Mycobacterium tuberculosis

Cilian Ó Maoldomhnaigh, Donal J Cox, J.J. Phelan et al. · Frontiers in Immunology · 2021 · 65 citations · Full text

Inhibiting Histone Deacetylases in Human Macrophages Promotes Glycolysis, IL-1β, and T Helper Cell Responses to Mycobacterium tuberculosis

Donal J Cox, Amy M. Coleman, Karl M Gogan et al. · Frontiers in Immunology · 2020 · 49 citations · Full text

Desferrioxamine Supports Metabolic Function in Primary Human Macrophages Infected With Mycobacterium tuberculosis

J.J. Phelan, Kate McQuaid, Colin Kenny et al. · Frontiers in Immunology · 2020 · 40 citations · Full text

The Iron Chelator Desferrioxamine Increases the Efficacy of Bedaquiline in Primary Human Macrophages Infected with BCG

Christina Cahill, Fiona O’Connell, Karl M Gogan et al. · International Journal of Molecular Sciences · 2021 · 16 citations · Full text

Antibiotic Adjuvant, Immunology, Antimicrobial Chemotherapy +22

Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis-dependent functional plasticity

Donal J Cox, Sarah A. Connolly, Cilian Ó Maoldomhnaigh et al. · eLife · 2024 · 11 citations · Full text