Hiroaki Okazaki

Identification of Liver X Receptor-Retinoid X Receptor as an Activator of the Sterol Regulatory Element-Binding Protein 1c Gene Promoter

Tomohiro Yoshikawa, Hitoshi Shimano, Michiyo Amemiya-Kudo et al. · Molecular and Cellular Biology · 2001 · 526 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +16

Polyunsaturated Fatty Acids Suppress Sterol Regulatory Element-binding Protein 1c Promoter Activity by Inhibition of Liver X Receptor (LXR) Binding to LXR Response Elements

Tomohiro Yoshikawa, Hitoshi Shimano, Naoya Yahagi et al. · Journal of Biological Chemistry · 2002 · 419 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Transcriptional activities of nuclear SREBP-1a, -1c, and -2 to different target promoters of lipogenic and cholesterogenic genes

Michiyo Amemiya-Kudo, Hitoshi Shimano, Alyssa H. Hasty et al. · Journal of Lipid Research · 2002 · 394 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

A Crucial Role of Sterol Regulatory Element-binding Protein-1 in the Regulation of Lipogenic Gene Expression by Polyunsaturated Fatty Acids

Naoya Yahagi, Hitoshi Shimano, Alyssa H. Hasty et al. · Journal of Biological Chemistry · 1999 · 367 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Absence of Sterol Regulatory Element-binding Protein-1 (SREBP-1) Ameliorates Fatty Livers but Not Obesity or Insulin Resistance in Lep/Lep Mice

Naoya Yahagi, Hitoshi Shimano, Alyssa H. Hasty et al. · Journal of Biological Chemistry · 2002 · 367 citations · Full text

Life Sciences, Biochemistry, Endocrinology +15