Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion

Jing Zhou, Shi-Hao Tan, Valérie Nicolas, +6

Cell Research

Cell AutophagyMitophagySignal TransductionMtorc1 SuppressionAutophagosome-lysosome Fusion +10

Self-assembling manifolds in single-cell RNA sequencing data

Alexander J. Tarashansky, Yuan Xue, Pengyang Li, +2

eLife

A single-parasite transcriptional atlas of Toxoplasma Gondii reveals novel control of antigen expression

Yuan Xue, Terence C. Theisen, Suchita Rastogi, +3

eLife

Single-cell analysis of Schistosoma mansoni identifies a conserved genetic program controlling germline stem cell fate

Pengyang Li, Dania Nanes Sarfati, Yuan Xue, +4

Nature Communications

Discovery of Novel Dual Histone Deacetylase and Mammalian Target of Rapamycin Target Inhibitors as a Promising Strategy for Cancer Therapy

Yong Chen, Yuan Xue, Wanhua Zhang, +8

Journal of Medicinal Chemistry

Differential Impacts on Host Transcription by ROP and GRA Effectors from the Intracellular Parasite Toxoplasma gondii

Suchita Rastogi, Yuan Xue, Stephen R. Quake, +1

mBio

Single-cell profiling identifies ACE ⁺ granuloma macrophages as a nonpermissive niche for intracellular bacteria during persistent <i>Salmonella</i> infection

Trung H.M. Pham, Yuan Xue, Susan Brewer, +3

Science Advances

The Complete Maternally and Paternally Inherited Mitochondrial Genomes of a Freshwater Mussel Potamilus alatus (Bivalvia: Unionidae)

Hai B. Wen, Zhe Cao, Dan Hua, +5

PLoS ONE

BiologyPhylogeneticsMolecular EcologyComparative GenomicsGenetics +13

The RpoE Stress Response Pathway Mediates Reduction of the Virulence of Enteropathogenic Escherichia coli by Zinc

Yuan Xue, Jossef F. Osborn, Anand Panchal, +1

Applied and Environmental Microbiology

Microbial ToxinMedical MicrobiologyEpec LeeMicrobial PathogensMedicine +13

Heterologous reporter expression in the planarian Schmidtea mediterranea through somatic mRNA transfection

Richard Nelson Hall, Uri Weill, Leonard Drees, +12

Cell Reports Methods