P. T. Ravi Rajagopalan

Network of coupled promoting motions in enzyme catalysis

Pratul K. Agarwal, Salomon R. Billeter, P. T. Ravi Rajagopalan et al. · Proceedings of the National Academy of Sciences · 2002 · 459 citations · Full text

Hydride Transfer, Protein Fold, Aldo-keto Reductase +10

Interaction of dihydrofolate reductase with methotrexate: Ensemble and single-molecule kinetics

P. T. Ravi Rajagopalan, Zhiquan Zhang, Lynn McCourt et al. · Proceedings of the National Academy of Sciences · 2002 · 290 citations · Full text

Tunneling and Coupled Motion in the <i>Escherichia </i><i>coli</i> Dihydrofolate Reductase Catalysis

Renatus Sikorski, Lin Wang, Kelli A Markham et al. · Journal of the American Chemical Society · 2004 · 192 citations

Preclinical Characteristics of the Hepatitis C Virus NS3/4A Protease Inhibitor ITMN-191 (R7227)

Scott D. Seiwert, Steven W. Andrews, Yutong Jiang et al. · Antimicrobial Agents and Chemotherapy · 2008 · 173 citations · Full text

Biochemistry, Viral Hepatitis, Medicine +14

Coupling Interactions of Distal Residues Enhance Dihydrofolate Reductase Catalysis:  Mutational Effects on Hydride Transfer Rates

P. T. Ravi Rajagopalan, Stefan Lutz, Stephen J. Benkovic · Biochemistry · 2002 · 166 citations