Keith S. Kwak

Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival

Xiaolan Zhou, Jin Lin Wang, John Lu et al. · Cell · 2010 · 939 citations · Full text

Medicine, Cancer Biology, Oncology +14

Calmodulin-stimulated cyclic nucleotide phosphodiesterase (PDE1C) is induced in human arterial smooth muscle cells of the synthetic, proliferative phenotype.

Sergei D. Rybalkin, Karin Bornfeldt, W. K. Sonnenburg et al. · Journal of Clinical Investigation · 1997 · 133 citations · Full text

Life Sciences, Biochemistry, Cell Biology +13

Identification of Inhibitory and Calmodulin-binding Domains of the PDE1A1 and PDE1A2 Calmodulin-stimulated Cyclic Nucleotide Phosphodiesterases

William K. Sonnenburg, Dalia Seger, Keith S. Kwak et al. · Journal of Biological Chemistry · 1995 · 126 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Regulation of Protein Catabolism by Muscle-Specific and Cytokine-Inducible Ubiquitin Ligase E3α-II during Cancer Cachexia

Keith S. Kwak, Xiaolan Zhou, Vered Solomon et al. · Cancer Research · 2004 · 111 citations

Life Sciences, Biochemistry, Oncology +14

Phosphorylation of the 61-kDa Calmodulin-Stimulated Cyclic Nucleotide Phosphodiesterase at Serine 120 Reduces Its Affinity for Calmodulin

Vincent A. Florio, William K. Sonnenburg, Richard S. Johnson et al. · Biochemistry · 1994 · 59 citations

Life Sciences, Biochemistry, Molecular Biology +16