Enhanced association of mutant triosephosphate isomerase to red cell membranes and to brain microtubules

Ferenc Orosz, Gábor Wágner, Károly Liliom, +6

Proceedings of the National Academy of Sciences

Organization‐dependent effects of toxic bivalent ions

Károly Liliom, Gábor Wágner, Anita Pácz, +3

European Journal of Biochemistry

Distinct behavior of mutant triosephosphate isomerase in hemolysate and in isolated form: molecular basis of enzyme deficiency

Ferenc Orosz, Judit Oláh, Marco Alvarez, +9

Blood

Tubulin and microtubule are potential targets for brain hexokinase binding

Gábor Wágner, János Kovács, Péter Lőw, +2

FEBS Letters

Brain Hexokinase BindingNeurotransmitterCytoskeletonMitochondrial BiologyPurified Hexokinase +22

Discovery and Preclinical Characterization of 3-((4-(4-Chlorophenyl)-7-fluoroquinoline-3-yl)sulfonyl)benzonitrile, a Novel Non-acetylenic Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulator for Psychiatric Indications

János Galambos, Attila Bielik, Mikhail Krasavin, +20

Journal of Medicinal Chemistry

Psychiatric IndicationsHigh ThroughputPsychopharmacologyPharmacotherapySocial Sciences +18

Combined Enhancement of Microtubule Assembly and Glucose Metabolism in Neuronal Systems in Vitro: Decreased Sensitivity to Copper Toxicity

Károly Liliom, Gábor Wágner, János Kovács, +4

Biochemical and Biophysical Research Communications

BiochemistryNeurophysiologyCopper ToxicityBioactive MetalPhysiology +9

Carbamoyloximes as novel non-competitive mGlu5 receptor antagonists

János Galambos, Gábor Wágner, Katalin Nógrádi, +17

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyBiochemistryFunctional SelectivityMedicineMechanism Of Action +4

4-Aryl-3-arylsulfonyl-quinolines as negative allosteric modulators of metabotropic GluR5 receptors: From HTS hit to development candidate

János Galambos, György Domány, Katalin Nógrádi, +13

Bioorganic & Medicinal Chemistry Letters

Negative Allosteric ModulatorsSignal TransductionG Protein-coupled ReceptorMetabotropic Glur5 ReceptorsDevelopment Candidate +7

Hit-to-lead optimization of disubstituted oxadiazoles and tetrazoles as mGluR5 NAMs

Gábor Wágner, Csaba Wéber, O. Nyéki, +14

Bioorganic & Medicinal Chemistry Letters

Chemical EngineeringEngineeringMedicineOrganic ChemistryChemistry +3

Thieno[2,3-b]pyridines as negative allosteric modulators of metabotropic GluR5 receptors: Lead optimization

Katalin Nógrádi, Gábor Wágner, György Domány, +13

Bioorganic & Medicinal Chemistry Letters