Shanshan Deng

Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy

Souvik Banerjee, Kinsie E. Arnst, Yuxi Wang et al. · Journal of Medicinal Chemistry · 2018 · 107 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer

Mauricio S. Caetano, Maya Hassane, Hieu T. Van et al. · Nature Communications · 2018 · 73 citations · Full text

Medicine, Immunology, Oncology +17

Tanshinone IIA Protects Against Cerebral Ischemia Reperfusion Injury by Regulating Microglial Activation and Polarization via NF-κB Pathway

Zhibing Song, Jingjing Feng, Qian Zhang et al. · Frontiers in Pharmacology · 2021 · 58 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Design, Synthesis, and Biological Evaluation of Stable Colchicine-Binding Site Tubulin Inhibitors 6-Aryl-2-benzoyl-pyridines as Potential Anticancer Agents

Hao Chen, Shanshan Deng, Najah Albadari et al. · Journal of Medicinal Chemistry · 2021 · 55 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

An Orally Available Tubulin Inhibitor, VERU-111, Suppresses Triple-Negative Breast Cancer Tumor Growth and Metastasis and Bypasses Taxane Resistance

Shanshan Deng, Raisa I. Krutilina, Qinghui Wang et al. · Molecular Cancer Therapeutics · 2019 · 48 citations · Full text

Medicine, Oncology, Pharmacology +17