Uwe Gritzan

Femtomolar Fab binding affinities to a protein target by alternative CDR residue co-optimization strategies without phage or cell surface display

Christian Votsmeier, Hanna Plittersdorf, Oliver Hesse et al. · mAbs · 2012 · 25 citations · Full text

Diagnostic Antibody Discovery, Immunocytochemical Technique, Protein Assembly +25

Glycoengineered factor IX variants with improved pharmacokinetics and subcutaneous efficacy

A.R. Brooks, Davin Sim, Uwe Gritzan et al. · Journal of Thrombosis and Haemostasis · 2013 · 18 citations · Full text

Autoimmune Disease, Pharmacology, Pharmacotherapy +2

Selective depletion of tumor-infiltrating regulatory T cells with BAY 3375968, a novel Fc-optimized anti-CCR8 antibody

Helge G. Roider, Sabine Hoff, Su-Yi Tseng et al. · Clinical and Experimental Medicine · 2024 · 16 citations · Full text

Modular Protein Expression Toolbox (MoPET), a standardized assembly system for defined expression constructs and expression optimization libraries

E. Weber, Jörg Birkenfeld, Jürgen K. Franz et al. · PLoS ONE · 2017 · 12 citations · Full text

Engineering, Protein Assembly, Molecular Biology +24

Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2)

Julia Huetter, Uwe Gritzan, Ilona Gutcher et al. · Cancer Immunology Research · 2020 · 11 citations