Mutant p53 improves cancer cells’ resistance to endoplasmic reticulum stress by sustaining activation of the UPR regulator ATF6

Daria Sicari, Marco Fantuz, Arianna Bellazzo, +8

Oncogene

Mutant P53Tumor BiologyUpr Regulator Atf6Cell RegulationMedicine +11

Mutant p53 potentiates the oncogenic effects of insulin by inhibiting the tumor suppressor DAB2IP

Elena Valentino, Arianna Bellazzo, Giulio Di Minin, +7

Proceedings of the National Academy of Sciences

Oncogenic EffectsMetabolic RemodelingInsulin SignalingTumor BiologyMutant P53 +14

The lncRNA H19 positively affects the tumorigenic properties of glioblastoma cells and contributes to NKD1 repression through the recruitment of EZH2 on its promoter

Barbara Fazi, Sabrina Garbo, Nicola Toschi, +10

Oncotarget

Neuro-oncologySystems BiologyGliomaOncogenic AgentLncrna H19 +13

Cell-autonomous and cell non-autonomous downregulation of tumor suppressor DAB2IP by microRNA-149-3p promotes aggressiveness of cancer cells

Arianna Bellazzo, Giulio Di Minin, Elena Valentino, +16

Cell Death and Differentiation

Tumor BiologyMicrorna-149-3p PromotesMedicineTumor Suppressor Dab2ipMicrorna Detection +7

The transcriptome and miRNome profiling of glioblastoma tissues and peritumoral regions highlights molecular pathways shared by tumors and surrounding areas and reveals differences between short-term and long-term survivors

Barbara Fazi, Armando Felsani, Luigi Grassi, +12

Oncotarget

Reflux of Endoplasmic Reticulum proteins to the cytosol inactivates tumor suppressors

Daria Sicari, Federica Grazia Centonze, Raphaël Pineau, +9

EMBO Reports

A virtuous cycle operated by ERp44 and ERGIC-53 guarantees proteostasis in the early secretory compartment

Tiziana Tempio, Andrea Orsi, Daria Sicari, +4

iScience

Extracellular AGR3 regulates breast cancer cells migration via Src signaling

Joanna Obacz, Lucia Sommerová, Daria Sicari, +8

Oncology Letters

Systems BiologySrc Kinase SignalingAgr ProteinsBreast OncologyCell Regulation +13

IRE1 endoribonuclease signaling promotes myeloid cell infiltration in glioblastoma

Joanna Obacz, Jérôme Archambeau, Élodie Lafont, +28

Neuro-Oncology

miR-331-3p is involved in glucocorticoid resistance reversion by rapamycin through suppression of the MAPK signaling pathway

Marianna Lucafò, Daria Sicari, Andrea Chicco, +11

Cancer Chemotherapy and Pharmacology