Trisha S. Smith

Elevated reactive oxygen species and antioxidant enzyme activities in animal and cellular models of Parkinson's disease

David S. Cassarino, Christopher P. Fall, Russell H. Swerdlow et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 1997 · 265 citations

Oxysterol, Reactive Oxygen Species, Biochemistry +10

Neurotoxic Aβ peptides increase oxidative stress <i>in vivo</i> through NMDA‐receptor and nitric‐oxide‐synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition <i>in vitro</i>

Janice K. Parks, Trisha S. Smith, Patricia A. Trimmer et al. · Journal of Neurochemistry · 2001 · 195 citations

Pramipexole Reduces Reactive Oxygen Species Production In Vivo and In Vitro and Inhibits the Mitochondrial Permeability Transition Produced by the Parkinsonian Neurotoxin Methylpyridinium Ion

David S. Cassarino, Christopher P. Fall, Trisha S. Smith et al. · Journal of Neurochemistry · 1998 · 184 citations

Dopamine Neurons from Transgenic Mice with a Knockout of the p53 Gene Resist MPTP Neurotoxicity

Patricia A. Trimmer, Trisha S. Smith, Anthony B. Jung et al. · Neurodegeneration · 1996 · 131 citations

Molecular Neuroscience, Medicine, Neurotransmitter +12

Mitochondrial toxins in models of neurodegenerative diseases. I: in vivo brain hydroxyl radical production during sytemic MPTP treatment or following microdialysis infusion of methylpyridinium or azide ions

Trisha S. Smith, James P. Bennett · Brain Research · 1997 · 130 citations

Neurodegenerative Diseases, Biochemistry, Mitochondrial Function +12