Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites

Tao Long, Michael Hicks, Hung‐Chun Yu, +19

Nature Genetics

Allelic VariantSequencingEngineeringMedicineGenetics +11

The Structure–Function Linkage Database

Eyal Akiva, Shoshana Brown, Daniel E. Almonacid, +16

Nucleic Acids Research

Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imaging

Ying‐Chen Claire Hou, Hung‐Chun Yu, Rick Martin, +24

Proceedings of the National Academy of Sciences

Porting the synthetic D‐glucaric acid pathway from <i>Escherichia coli</i> to <i>Saccharomyces cerevisiae</i>

Amita Gupta, Michael Hicks, Shawn P. Manchester, +1

Biotechnology Journal

Miox EnzymeEngineeringMetabolic NetworksBiosynthesisGrowth Rate +15

An unsupervised learning approach to identify novel signatures of health and disease from multimodal data

Ilan Shomorony, Elizabeth T. Cirulli, Lei Huang, +16

Genome Medicine

The evolution of function in strictosidine synthase‐like proteins

Michael Hicks, Alan E. Barber, LesleyAnn Giddings, +3

Proteins Structure Function and Bioinformatics

Active SitesMolecular BiologyAnalytical UltracentrifugationExponential GrowthProtein Synthesis +14

Functional characterization of 3D protein structures informed by human genetic diversity

Michael Hicks, István Bartha, Julia di Iulio, +2

Proceedings of the National Academy of Sciences

Structural Intolerance AnalysisStructural BioinformaticsBiomolecular Structure PredictionGeneticsMolecular Biology +20

Establishing the involvement of the novel gene<i>AGBL5</i>in retinitis pigmentosa by whole genome sequencing

Kari Branham, Hiroko Matsui, Pooja Biswas, +12

Physiological Genomics

Using unsupervised learning for feature detection in a coal mine roof

Roger L. King, Michael Hicks, Stephen P. Signer

Engineering Applications of Artificial Intelligence

Machine VisionImage AnalysisData ScienceMachine LearningPattern Recognition +10

Rational design of thiolase substrate specificity for metabolic engineering applications

Brian M. Bonk, Yekaterina Tarasova, Michael Hicks, +2

Biotechnology and Bioengineering

Thiolase Substrate SpecificityEngineeringMetabolic NetworksThiolase MutantsMetabolic Model +15