David A.J. Lecky

Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteria

Rebecca A. Drummond, Jigar V. Desai, Emily Ricotta et al. · Cell Host & Microbe · 2022 · 125 citations · Full text

Systemic Fungal Infection, Antibiotics, Antimicrobial Stewardship +10

Antigen and checkpoint receptor engagement recalibrates T cell receptor signal strength

Thomas A.E. Elliot, Emma Jennings, David A.J. Lecky et al. · Immunity · 2021 · 62 citations · Full text

Nur77-Tempo mice reveal T cell steady state antigen recognition

Thomas A.E. Elliot, Emma Jennings, David A.J. Lecky et al. · Discovery Immunology · 2022 · 26 citations · Full text

Salmonella cancer therapy metabolically disrupts tumours at the collateral cost of T cell immunity

Alastair Copland, Gillian M. Mackie, Lisa Scarfe et al. · EMBO Molecular Medicine · 2024 · 11 citations · Full text